Remove skin from chicken and trim fat. Place all the chicken in a large bowl. In a medium bowl, mix together buttermilk, hot sauce, and 2 teaspoons salt. Pour mixture over chicken, making sure all pieces are coated. Cover and refrigerate for at least 1 hour or overnight.
In a shallow bowl or pie dish, combine flour, Lawry’s seasoning salt, garlic powder, onion powder, and a little black pepper. Working with one thigh at a time, remove chicken from buttermilk, shaking off excess buttermilk. Place in flour mixture, turning to coat well.
Preheat air-fryer to 400 degrees. Spray the air-fryer basket with cooking spray. Place coated chicken in basket. If you have a small air-fryer, you’ll need to cook in batches so you don’t overcrowd the basket. Cook until chicken is golden and cooked through about 20 minutes. flip halfway through, if desired. Repeat with remaining chicken.
Heat oven to low heat and put cooked chicken on a baking pan between batches to stay warm.